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Calcium fragment 311/20/2023 ![]() HADD and CPPD crystal deposition have a distinct appearance on radiograph.The clinical manifestations of calcifications may sometimes mimic septic arthritis or sarcoma.A musculoskeletal MRI study must always be correlated with a radiograph.Calcifications have to be differentiated form ossification and foreign body.Soft tissue calcification can be caused by secondary tumoural calcinosis from renal insufficiency, or collagen vascular diseases and by vascular calcifications, either arterial or venous (phlebolith). In most cases, intra-articular calcifications are caused by calcium pyrophosphate dihydrate (CPPD) crystal deposition disease. Intra-tendon calcifications are most frequently associated with hydroxyapatite deposition disease (HADD). Each location has a specific short differential diagnosis, with minimal further investigation necessary. One should first differentiate a calcification from an ossification or a foreign body and then locate the calcification correctly. ![]() The goal of this article is to help radiologists to make the correct diagnosis when faced with an extraosseous musculoskeletal calcification. The bounty icons will look like the ones below, starting with the one on the left and progressing through to the right.Musculoskeletal calcifications are frequent on radiographs and sometimes problematic. They will appear under the " Bounties" area in the "Quests" section on the right side, but not as an actual quest. The first bounty is automatically given to you while fighting in the Court of Oryx and the others replace their predecessors when you complete them. Note: This is rewarded from a bounty chain, not an actual questline.
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